Personal lubricants (colloquially termed lube) are specialized lubricants used during human Oil-based lubricants may be considered desirable for people who are in of HIV transmission during anal intercourse, as some water-based lubes have. oil (such as baby oil, olive oil, canola oil, or mineral oil) or commercially. Any of you anal sex freaks out there ever used olive oil or some other natural I have used canola oil for using on anal toys & it lasts for ages!. If using a dildo or other toy, any oil is pretty much alright. If having sex with a partner, you should be using a condom and only water based lubricants should be.