Treatment options for pruritis ani: eliminate irritants and general ideally be in the squatting positions so the anal canal is washed of retained faeces. alternatively, petroleum ointment can be applied after washing. Learn the top 5 causes (and remedies) of anal itching. If there's itching, you can use an over-the-counter or prescription hemorrhoid creams. Anal itch, also known as pruritus ani, is an irritating, itchy sensation around Anal itch also can be triggered by over-the-counter medications.